The Natural History of Infantile Spasms

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The natural history of infantile spasms.

The claim of Sorel to have improved the outlook for children with the syndrome of infantile spasms ('lightning spasms') and mental retardation by the use of corticotrophin (Sorel and Dusaucy-Bauloye, 1958; Sorel, 1959) has aroused widespread interest, and first reports have been enthusiastic (Low, 1958, 1959; Stamps, Gibbs, Rosenthal and Gibbs, 1959). Cortisone has also been said to be effectiv...

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Infantile spasms.

Infantile spasms constitute both a distinctive seizure type and an age-specific epilepsy syndrome that have been extensively described for over a century. Standardization of the classification of infantile spasms has evolved, culminating in recent recommendations for separately recognizing and distinguishing the seizure type (spasms or epileptic spasms) and the epilepsy syndrome of infantile sp...

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Infantile spasms.

Overview Infantile spasms, also known as West syndrome, is a catastrophic childhood epilepsy with seizures that are difficult to control; it is associated with mental retardation. It usually has an onset during the first year of life, and typically between 4 and 8 months. Early recognition, careful diagnostic evaluation, and proper treatment may allow some children to attain seizure control and...

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The latest on infantile spasms.

PURPOSE OF REVIEW This article reviews the most significant advances in the field of infantile spasm during the past year, with emphasis on best practise for treatment, and on some new etiological genetic and metabolic causes for the spasms, and new advances in the knowledge of tuberous sclerosis. RECENT FINDINGS Up-to-date information comparing corticotrophin, oral steroids and vigabatrin sh...

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Infantile spasms Richard

Infantile spasms represent a seizure disorder with unique clinical and electroencephalographic (hypsarrhythmia) features and a poor prognosis including chronic intractable epilepsy and psychomotor retardation. The association of spasms and hypsarrhythmia, with or without mental retardation, defines West's syndrome. West's syndrome is not uncommon; the incidence is considered to be 0 16-0-42 per...

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ژورنال

عنوان ژورنال: Archives of Disease in Childhood

سال: 1961

ISSN: 0003-9888,1468-2044

DOI: 10.1136/adc.36.185.17